RNA, Messenger, Editing

Medical Condition:
RNA, Messenger, Editing

A process that changes the nucleotide sequence of mRNA from that of the DNA template encoding it. Some major classes of RNA editing are as follows: 1) the conversion of cytosine to uracil in mRNA; 2) the addition of variable number of guanines at pre-determined sites; and 3) the addition and deletion of uracils, templated by guide-RNAs (RNA, GUIDE).