Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase

Medical Condition:
Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase

A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC 1.14.11.4.

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