Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer

Medical Condition:
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer

The main active constituent of the resin from the roots of may apple or mandrake (Podophyllum peltatum and P. emodi). It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.