Phosphoenolpyruvate Carboxykinase, GTP-Dependent

Medical Condition:
Phosphoenolpyruvate Carboxykinase, GTP-Dependent

An enzyme of the lyase class that catalyzes the conversion of GTP and oxaloacetate to GDP, phosphoenolpyruvate, and carbon dioxide. This reaction is part of gluconeogenesis in the liver. The enzyme occurs in both the mitochondria and cytosol of mammalian liver. (From Dorland, 27th ed) EC 4.1.1.32.

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