Phenylalanine Ammonia Lyase

Medical Condition:
Phenylalanine Ammonia Lyase

An enzyme that catalyzes the deamination of L-phenylalanine to form trans-cinnamate and ammonia. It may also act on L-tyrosine. Since the enzyme deprives neoplastic tissue of phenylalanine, it has been used experimentally in the treatment of acute lymphoblastic leukemia. The enzyme is obtained from many plants. EC 4.3.1.5.