NAD-Dependent Hydroxymethylglutaryl-CoA Reductases

Medical Condition:
NAD-Dependent Hydroxymethylglutaryl-CoA Reductases

Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH.

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