Guanylyl Cyclase-Activating Factor Synthase

Medical Condition:
Guanylyl Cyclase-Activating Factor Synthase

An enzyme that catalyzes the conversion of L-arginine, NADPH, and oxygen to citrulline, nitric oxide, and NADP+. The enzyme found in brain, but not that induced in lung or liver by endotoxin, requires calcium. (From Enzyme Nomenclature, 1992) EC 1.14.13.39.