Epidermal Growth Factor Related Transforming Growth Factor

Medical Condition:
Epidermal Growth Factor Related Transforming Growth Factor

Factor isolated in a variety of tissues including epithelium, and maternal decidua. It is closely related to EPIDERMAL GROWTH FACTOR and binds to the EGF receptor. TGF-alpha acts synergistically with TGF-beta in inducing phenotypic transformation, but its physiological role is unknown.