Dihydro-Orotate Oxidase

Medical Condition:
Dihydro-Orotate Oxidase

An enzyme that in the course of pyrimidine biosynthesis, catalyzes the oxidation of dihydro-orotic acid to orotic acid utilizing oxygen as the electron acceptor. This enzyme is a flavoprotein which contains both FLAVIN-ADENINE DINUCLEOTIDE and FMN as well as iron-sulfur centers. EC 1.3.3.1.