Medical Condition:
Cytochrome P-450(17 alpha)
A steroid hydroxylase system found in the microsomal membrane of the steroid-hormone producing tissues. It catalyzes the 17-hydroxylation of steroids, such as progesterone or pregnenolone in the presence of NADPH and molecular oxygen. This is an important step in the biosynthesis of steroid hormones. EC 1.14.99.9.