Complement 5

Medical Condition:
Complement 5

The fifth component in the complement reaction sequence, probably exists in a complex with C6 and C7. It is a beta-globulin with a sedimentation coefficient of 10, serum concentration of 75 micrograms/ml and molecular weight of 180,000. It is activated by C423 and releases fragments with anaphylatoxic, chemotactic, and histamine-releasing actions and affecting smooth muscle.